Illustration of the antibiotic zosurabalpin (red) trapping a lipopolysaccharide molecule (orange) in an intermembrane transporter (blue). This interrupts the assembly of the outer membrane of the bacterial cell wall, leading to the death of the bacterium. The discovery of zosurabalpin was announced in January 2024 and was the first new antibiotic shown to be effective against Carbapenem-resistant Acinetobacter baumannii (CRAB) in 50 years.
| px | px | dpi | = | cm | x | cm | = | MB |
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Creative#:
TPG34674584
Source:
達志影像
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RF
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須由TPG 完整授權
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3dimensional3damrantibacterialantibioticantibioticresistanceantimicrobialresistanceartworkbacteriabacterialbacteriologicalbacteriologybiochemicalbiochemistrybiomedicineblockingcellmembranecellwallcgidruggramnegativegram-negativegraybackgroundgreybackgroundillustrationintermembranetransporterlipopolysaccharidelpsmcpmedicalmedicinemicrobiologicalmicrobiologymolecularmodelmoleculemoleculesmultidrugresistancemulti-drugresistanceno-onenobodyoutermembranepharmaceuticalspharmacologicalpharmacologyproteinstructuretetheredmacrocyclicpeptidethreedimensionaltraptreatmentzosurabalpin
33damrantibacterialantibioticantibioticantimicrobialartworkbackgroundbackgroundbacteriabacterialbacteriologicalbacteriologybiochemicalbiochemistrybiomedicineblockingcellcellcgidimensionaldimensionaldrugdruggramgram-negativegraygreyillustrationintermembranelipopolysaccharidelpsmacrocyclicmcpmedicalmedicinemembranemembranemicrobiologicalmicrobiologymodelmolecularmoleculemoleculesmultimulti-drugnegativeno-onenobodyouterpeptidepharmaceuticalspharmacologicalpharmacologyproteinresistanceresistanceresistanceresistancestructuretetheredthreetransportertraptreatmentwallzosurabalpin
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