The History of the True Cross or The Legend of the True Cross is a sequence of frescoes painted by Piero della Francesca in the Basilica of San Francesco in Arezzo. It is his largest work; and generally considered one of his finest; and an early Renaissance masterpiece.

Its theme; derived from the popular 13th century book on the lives of saints by Jacopo da Voragine; the Golden Legend; is the triumph of the True Cross - the legend of the wood from the Garden of Eden becoming the Cross on which Jesus Christ was crucified. This work demonstrates Piero's advanced knowledge of perspective and colour; his geometric orderliness and skill in pictorial construction.