Jardine Matheson & Co., later Jardine Matheson & Co. Ltd., forerunner of today's Jardine Matheson Holdings, was a Far Eastern trading company founded in 1832 with Scotsmen William Jardine and James Matheson as senior partners. Trading in opium, cotton, tea, silk and a variety of other goods, from its early beginnings in Canton (modern day Guangzhou), in 1844 the firm established its head office in the new British colony of Hong Kong then proceeded to expand all along the China Coast.

By the end of the nineteenth century, Jardine, Matheson & Co. had become the largest of the foreign trading companies in the Far East and had expanded its activities into sectors including shipping, cotton mills and railway construction.

Further growth occurred in the early decades of the twentieth century with new cold storage, packing and brewing businesses while the firm also became the largest cotton spinner in Shanghai.

After the founding of the People's Republic of China on 1 October 1949, doing business in the country became increasingly problematic. As a result, foreign businesses gradually withdrew from the mainland with Jardines leaving in 1954 to reconsolidate its business in Hong Kong. The firm would not return to mainland China until 1979, following the reform and opening up of the country.